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Several epidemiologic studies have shown an association between markers of inflammation and oxidative stress and type 2 diabetes and other metabolic conditions
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The FDA’s own reviewers concluded there is “insufficient evidence of effectiveness to support use of semax (free base) or semax acetate for cerebral ischemia, migraine, or trigeminal neuralgia.” They called the substance “not well-characterized from the physical and chemical characterization perspective.” The strongest human result they cited was a small migraine study in which four of twelve subjects, or 33%, reported cessation of headache pain
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