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[DOI] [PMC free article] [PubMed] [Google Scholar] 66.Kadiiska M.B., Gladen B.C., Baird D.D., Germolec D., Graham L.B., Parker C.E., Nyska A., Wachsman J.T., Ames B.N., Basu S., Brot N., Fitzgerald G.A., Floyd R.A., George M., Heinecke J.W., Hatch G.E., Hensley K., Lawson J.A., Marnett L.J., Morrow J.D., Murray D.M., Plastaras J., Roberts L.J., 2nd, Rokach J., Shigenaga M.K., Sohal R.S., Sun J., Tice R.R., Van Thiel D.H., Wellner D., Walter P.B., Tomer K.B., Mason R.P., Barrett J.C

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Thus, since SIRT1 deacetylase activity relies on NAMPT-mediated NAD + biosynthesis, SIRT1 has been hypothesized to link cellular metabolism to the circadian clockwork