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[DOI] [PMC free article] [PubMed] [Google Scholar] 107.Chen Y.C., Lu R.B., Peng G.S., Wang M.F., Wang H.K., Ko H.C., Chang Y.C., Lu J.J., Li T.K., Yin S.J

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This limitation is similar to that of the two autophagy inhibitors currently applied in the clinic, chloroquine (CQ) and HCQ—the clinical trials based on these drugs targeting autophagy have been largely limited to cancer therapy, again due to the high concentrations required for their effectiveness [169, 170]