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Mechanisms of Hyperhomocysteinemia Induced Skeletal Muscle Myopathy after Ischemia in the CBS−/+ Mouse Model

This process is facilitated by histone acetyltransferases, which add acetyl groups, while histone deacetylases (HDACs) remove them, leading to chromatin compaction and suppression of gene expression

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Although supplementations, especially with L-alanyl-L-glutamine, increased glutamine concentrations, there were no differences between groups in the time to exhaustion, indicating that neither glutamine nor L-alanyl-L-glutamine supplementation improved physical performance