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Interestingly, the decrease in new-onset macroalbuminuria (and of the composite outcome that contained it) was apparent in both patients on and off SGLT2 inhibitors, although the difference was only statistically significant for patients off SGLT2 inhibitors, which were the larger group [HR 0.57 (95% CI 0.40–0.81) for the composite endpoint and HR 0.37 (95% CI 0.21–0.65) for new-onset macroalbuminuria]
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