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4 Standard therapy for persistent asthma has long centered on inhaled corticosteroids (ICS) to suppress airway inflammation, often combined with inhaled long-acting β 2 -agonists (LABA) for bronchodilation

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Potential clues that WASF3 may be involved in the immune system come from early observations that JAK2/STAT3 pathway can regulate WASF3 through both transcriptional and protein phosphorylation mechanisms, whereas overexpression of WASF3 alone activates the NFKB pathway (22, 104)

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