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Vitamin B12 allergy manifesting as lymphomatoid contact dermatitis | Semantic Scholar
Methylcobalamin is preferred over cyanocobalamin (the synthetic form) in many clinical settings because it is the metabolically active coenzyme form of B12, meaning the body can utilise it immediately without further conversion
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Also, individuals with COMT defects can be at higher risk for accumulating too much peroxynitrites which builds up in their bodies, causing stiffness and muscle pain or “brain fog” and cardiovascular problems
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