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Retatrutide Retatrutide (triple GIP/GLP-1/glucagon agonist) research peptide — high-purity lyophilized powder, third-party tested with a Certificate of Analysis (COA)
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LPS from dysbiotic Gram-negative bacteria prime the TLR4/NF-κB pathway, extracellular ATP released during sleep disruption activates P2X7R, and subsequent NLRP3-driven IL-1β secretion amplifies neuroinflammation and suppresses GABAergic transmission—hallmarks of insomnia and hyperarousal (69–71)
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